Lastest Update: 10th Oct 2023
Selected publications
Herein are displayed some published articles, should one wish to obtain the complete information, reference can be made to my Google Scholar page or ResearchGate.
First/Corresponding Authorship
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Integration of TMB and tumor heterogeneity identify an immunologic subtype of melanoma with favorable survival.
Gao Y, Yang C, He N, Wang J, Yang Y*. Oct 2020. Frontiers in Oncology -
Platform-independent approach for cancer detection from gene expression profiles of peripheral blood cells
Yang Y#, Zhang T#, Qu H, Xie B, Fang X. May 2020. Brief Bioinform. -
TRIM44 is indispensable for glioma cell proliferation and cell cycle progression through AKT/p21/p27 signaling pathway.
Zhou X#, Yang Y#, Ma P, Wang Na, Yang D, Tu Q, Sun B, Xiang T, Zhao X, Hou Z*, Fang X. Nov 2019. Journal of Neuro-Oncology -
GliomaDB: a Database of Integrating Glioma Precision Medicine Data.
Yang Y, Sui Y, Xie B, Qu H, Fang X. Aug 2018. Genomics Proteomics Bioinformatics. -
GSA: Genome Sequence Archive.
Wang Y#, Song F#, Zhu J#, Zhang S#, Yang Y#, Chen T, Tang B, Dong L, Ding N, Zhang Q, Bai Z, Dong X, Chen H, Sun M, Zhai S, Sun Y, Yu L, Lan L, Xiao J, Fang X, Lei H, Zhang Z, Zhao W. Feb 2017. Genomics Proteomics Bioinformatics -
miRNome Analysis of CML Cells.
Yang Y, Ding N, Dong X, Fang X. 2016. Methods Mol Biol.(Springer book) -
Whole genome nucleosome sequencing identifies novel types of forensic markers in degraded DNA samples.
Dong C#, Yang Y#, Li S, Yang Y, Zhang X, Fang X, Yan J, Cong B. May 2016. Sci Rep -
Databases and Web Tools for Cancer Genomics Study.
Yang Y, Dong X, Xie B, Ding N, Chen J, Li Y, Zhang Q, Qu H, Fang X. Feb 2015. Genomics Proteomics Bioinformatics -
Abraxane, the Nanoparticle Formulation of Paclitaxel Can Induce Drug Resistance by Up-Regulation of P-gp.
Zhao M#, Lei C#, Yang Y#, Bu X, Ma H, Gong H, Liu J, Fang X, Hu Z, Fang Q. Jul 2015. PLoS One -
Characterization of miRNomes in acute and chronic myeloid leukemia cell lines.
Xiong Q#, Yang Y#, Wang H, Li J, Wang S, Li Y, Yang Y, Cai K, Ruan X, Yan J, Hu S, Fang X. Apr 2014. Genomics Proteomics Bioinformatics -
Transcriptome Dynamics during Human Erythroid Differentiation and Development.
Yang Y#, Wang H#, Chang KH#, Qu H, Zhang Z, Xiong Q, Qi H, Cui P, Lin Q, Ruan X, Yang Y, Li Y, Shu C, Li Q, Wakeland EK, Yan J, Hu S, Fang X. Dec 2013. Genomics -
Few single nucleotide variations in exomes of human cord blood induced pluripotent stem cells.
Su RJ#, Yang Y#, Neises A, Payne KJ, Wang J, Viswanathan K, Wakeland EK, Fang X, Zhang XB. Apr 2013. PLoS One
Other Authorship
1. Xu Z, Cheng S, Qiu X, Wang X, Hu Q, Shi Y, Liu Y, Lin J, Tian J, Peng Y, Jiang Y, Yang Y, Ye J, Wang Y, Meng X, Li Z, Li H, Wang Y. A Pipeline for Sample Tagging of Whole Genome Bisulfite Sequencing Data Using Genotypes of Whole Genome Sequencing. Jun 2023, BMC Genomics (IF: 4.4)
2. Jiang J, Jin Z, Zhang Y, Peng L, Zhang Y, Zhu Z, Wang Y, Tong D, Yang Y, Wang J, Yang Y, Xiao K. Robust prediction of immune checkpoint inhibition therapy for non-small cell lung cancer. Apr 2021, Frontiers in Immunology (IF: 8.78)
3. Xie B, Yuan Z, Yang Y, Sun Z, Zhou S, Fang X. MOBCdb: a comprehensive database integrating multi-omics data on breast cancer for precision medicine. Breast Cancer Res Treat 2018. [Epub ahead of print]
4. BIG Data Center Members. The BIG Data Center:from deposition to integration to translation. Nucleic Acid Research. 2017 Nov;45(D1)D18-D24. doi: 10.1093/nar/gkw1060
5. Li Y, Zhang Q, Du Z, Lu Z, Liu S, Zhang L, Ding N, Bao B, Yang Y, Xiong Q, Wang H, Zhang Z, Qu H, Jia H, Fang X. MicroRNA 200a inhibits erythroid differentiation by targeting PDCD4 and THRB. Br J Haematol. 2017 Jan;176(1):50-64. doi: 10.1111/bjh.14377. Epub 2016 Oct 13.
6. Zhang Q, Ding N, Zhang L, Zhao X, Yang Y, Qu H, Fang X. Biological Databases for Hematology Research. Genomics Proteomics Bioinformatics. 2016 Dec;14(6):333-337. doi: 10.1016/j.gpb.2016.10.004. Epub 2016 Dec 11.
7. 张韬, 杨亚东, 方向东*. 应用于精准医学研究的转录组可变剪接分析. 发育医学电子杂志, 2016; 4(2): 83-89
8. 谢兵兵, 杨亚东, 方向东*. 整合分析多组学数据筛选疾病靶点的精准医学策略. 遗传, 2015; 37(7): 655-663
9. 李艳明, 杨亚东, 张昭军, 方向东*. 精准医学大数据的分析与共享. 中国医学前沿杂志, 2015; 7(6): 4-10
10. Li Y, Liu S, Sun H, Yang Y, Qi H, Ding N, Zheng J, Dong X, Qu H, Zhang Z, Fang X. MiR-218 Inhibits Erythroid Differentiation and Alters Iron Metabolism by Targeting ALAS2 in K562 Cells. Int J Mol Sci. 2015 Nov 26;16(12):28156-68.
11. Ding N, Wang S, Yang Q, Li Y, Cheng H, Wang J, Wang D, Deng Y, Yang Y, Hu S, Zhao H, Fang X. Deep sequencing analysis of microRNA expression in human melanocyte and melanoma cell lines. Gene. 2015 Nov 1;572(1):135-45.
12. Liang F, Qu H, Lin Q, Yang Y, Ruan X, Zhang B, Liu Y, Yu C, Zhang H, Fang X, Hao X. Molecular biomarkers screened by next-generation RNA sequencing for non-sentinel lymph node status prediction in breast cancer patients with metastatic sentinel lymph nodes. World J Surg Oncol. 2015 Aug 28;13:258.
13. Hu Y, Xiong Q, Yang Y, Wang H, Shu C, Xu W, Fang X, Hu S. Integrated analysis of gene expression and microRNA regulation in three leukemia-related lymphoblastic cell lines. Gene. 2015 Jun 10;564(1):39-52.
14. Wang H, Li Y, Wang S, Zhang Q, Zheng J, Yang Y, Qi H, Qu H, Zhang Z, Liu F, Fang X. Knockdown of transcription factor forkhead box O3 (FOXO3) suppresses erythroid differentiation in human cells and zebrafish. Biochem Biophys Res Commun. 2015 May 15;460(4):923-30.
15. Dong C, Yang Y, Yan J, et al. Evaluation of the protective capabilities of nucleosome STRs obtained by large-scale sequencing. Electrophoresis. 2015;36(14):1640-1650. doi:10.1002/elps.201400537
16. Zhao H#, Li Y#, Wang S#, Yang Y, Wang J, Ruan X, Yang Y, Cai K, Zhang B, Cui P, Yan J, Zhao Y, Wakeland EK3, Li Q, Hu S, Fang X. Whole Transcriptome RNA-seq Analysis: Tumorigenesis and Metastasis of Melanoma. Gene. 2014 Sep 15;548(2):234-43.
17. Wang Y#, Zhang Z#, Chi Y, Zhang Q, Xu F, Yang Z, Meng L, Yang S, Yan S, Mao A, Zhang J, Yang Y, Wang S, Cui J, Liang L, Ji Y, Han ZB, Fang X, Han ZC. Long-term cultured mesenchymal stem cells frequently develop genomic mutations but do not undergo malignant transformation. Cell Death Dis 2013; 4: e950
18. Xiong Q#, Zhang Z#, Chang KH#, Qu H, Wang H, Qi H, Li Y, Ruan X, Yang Y, Yang Y, Li Y, Sandstrom R, Sabo PJ, Li Q, Stamatoyannopoulos G, Stamatoyannopoulos JA, Fang X*. Comprehensive characterization of erythroid-specific enhancers in the genomic regions of human Kruppel-like factors. BMC Genomics. 2013 Aug 28;14:587.
19. Wang H#, Hu H#, Zhang Q, Yang Y, Li Y, Hu Y, Ruan X, Yang Y, Zhang Z, Shu C, Yan J, Wakeland EK, Li Q, Hu S, Fang X. Dynamic transcriptomes of human myeloid leukemia cells. Genomics 2013; 102: 250-6
20. Chang KH#, Fang X#, Wang H, Huang A, Cao H, Yang Y, Bonig H, Stamatoyannopoulos JA, Papayannopoulou T*. Epigenetic Modifications and Chromosome Conformations of the Beta Globin Locus throughout Development. Stem Cell Rev. 2013; 9(4):397-407.
21. Ma L, Nie L, Liu J, Zhang B, Song S, Sun M, Yang J, Yang Y, Fang X, Hu S, Zhao Y, Yu J. An RNA-seq-based Gene Expression Profiling of Radiation-induced Tumorigenic Mammary Epithelial Cells. Genomics Proteomics Bioinformatics. 2012; 10(6): 326-35.
22. Li Y#, Wang H#, Yang B#, Yang J, Ruan X, Yang Y, Wakeland EK, Li Q, Fang X*. Influence of Carbon Monoxide on Growth and Apoptosis of Human Umbilical Artery Smooth Muscle Cells and Vein Endothelial Cells. Int J Biol Sci. 2012; 8(10): 1431–1446.
Conference
1. Ma J, He N, Wang J, Wang L, Jin G, Lin R, Yang Y. CD8A and HAPLN3 expression profiling to reveal an immunologic subtype of bladder cancer with favorable survival. 2020. Journal of Clinical Oncology. American Society of Clinical Oncology
2. Fu, Zhichao and Liu, Shenghua and Wang, Jianfei and Zhang, Yiqun and Yang Y and Xu, Tianyuan and Anil, Shrestha and Yan, Yang and Li, Cheng and Zheng, Zongtai and others. Transcriptome analysis of low-risk and high-risk non-muscular invasive bladder cancer patients to reveal disease progression related genes. 2020. Journal of Clinical Oncology. American Society of Clinical Oncology
3. Yang, Chunhe and Zhao, Guodong and Wang, Jianfei and Wang, Lingyu and Jin, Ge and Lin, Rongbo and Yang Y. Integration of TMB and tumor heterogeneity identify an immunologic subtype of melanoma with favorable survival. 2020. Journal of Clinical Oncology. American Society of Clinical Oncology
4. Wang, Kun and Yang, Yang Y, Xiaoyu and Li, Juan and Bao, Quan and Wang, Hongwei and Jin, Kemin and Liu, Ming and Liu, Wei and Yan, Xiaoluan and others. Prognostic impact of mutation profiling in Chinese patients with colorectal liver metastases. 2020. Journal of Clinical Oncology. American Society of Clinical Oncology
5. Wang, Hai and Yang Y and Hongzhu, QU and Ruan, Xiuyan and Zhang, Zhaojun and Xiong, Qian and Qi, Heyuan and Stamatoyannopoulos, George and Stamatoyannopoulos, John A and Fang, Xiangdong. unctional Analysis of FOXO3A Involved in Erythroid Differentiation. 2012. Blood. American Society of Hematology
6. He, Ning and Wang, Jianfei and Wang, Lingyu and Jin, Ge and Lin, Rongbo and Yang Y. Metabolism of tumor cell in tumor micro environment assist immune escape. 2020. Journal of Clinical Oncology. American Society of Clinical Oncology
7. Yu, Yao and Lin, Rongbo and He, Ning and Yang Y and Jin, Ge and Wang, Jianfei. Correlation of tumor mutational burden, tumor microenvironment and alterations of driver genes in patients with NSCLC: A retrospective analysis. 2019. Journal of Clinical Oncology. American Society of Clinical Oncology
8. He, Ning and Zhang, Yiqun and Yang Y and Wang, Jianfei. Multi-omics prognosis predictive model of metastatic urothelial carcinoma (mUCs) with immunotherapy. 2021. Journal of Clinical Oncology. American Society of Clinical Oncology
9. Zhang, Yiqun and Zhao, Guodong and He, Ning and Wang, Lingyu and Wang, Jianfei and Jin, Ge and Lin, Rongbo and Yang Y. Robust prediction of immune checkpoint inhibition therapy for non-small cell lung cancer. 2020. Journal of Clinical Oncology. American Society of Clinical Oncology
10. Jia, Yuanyuan and He, Ning and Yang Y and Huang, Yuliang and Zhang, Xiaoyu and Fu, Zhichao and Xu, Xiaohong and Cao, Jianjun and Wang, Jianfei. Tumor mutation burden and immune microenvironment analysis of urothelial carcinoma. 2021. Journal of Clinical Oncology. American Society of Clinical Oncology
11. Li, Yanming and Liu, Shuge and Hongzhu, QU and Yang Y and Ding, Nan and Ruan, Xiuyan and Stamatoyannopoulos, George and Fang, Xiangdong. PDCD2 Knockdown Promoted Induced Erythroid Differentiation in TF-1 Cells. 2014. Blood. American Society of Hematology 12. Yang, Ping and Ji, Guanghui and Jiang, Qionghui and Lu, Zejun and Yu, Yao and Yang Y and Jin, Ge. Mutation profiles in circulating tumor DNA (ctDNA) to predict the efficacy of sorafenib treatment in patients with advanced hepatocellular carcinoma (HCC). 2019. Journal of Clinical Oncology. American Society of Clinical Oncology
13. Fu, Zhichao and Liu, Shenghua and Wang, Jianfei and He, Ning and Yang Y and Xu, Tianyuan and Anil, Shrestha and Yan, Yang and Li, Cheng and Zheng, Zongtai and others. RNA-seq analysis of non-muscular invasive bladder cancer to reveal different gene expression profiles between smoking and non-smoking patients. 2021. Journal of Clinical Oncology. American Society of Clinical Oncology